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UID:20260808T211033EDT-3144PxHmuu@132.216.98.100
DTSTAMP:20260809T011033Z
DESCRIPTION:Our last seminar of the semester is coming Thursday at 2:30 in 
 Purvis 24. Lauren Maxwell will lead our discussion on the following paper 
 of her choice. Free pdf is available from this link.\n\nA Longitudinal Stu
 dy of Vaginal Douching and Bacterial Vaginosis-A Marginal Structural Model
 ing Analysis\n	The etiology of bacterial vaginosis is unknown\, and there a
 re no long-term therapies for preventing this frequently recurring conditi
 on. Vaginal douching has been reported to be associated with bacterial vag
 inosis in observational studies. However\, this association may be due to 
 confounding by indication-that is\, confounding by women douching in respo
 nse to vaginal symptoms associated with bacterial vaginosis. The authors u
 sed marginal structural modeling to estimate the causal effect of douching
  on bacterial vaginosis risk while controlling for this confounding effect
 . In 1999-2002\, nonpregnant women (n = 3\,620) were recruited into a pros
 pective study when they visited one of 12 public health clinics in Birming
 ham\, Alabama\, for routine care. Participants were assessed quarterly for
  1 year. Bacterial vaginosis was based on a Nugent's Gram stain score of 7
  or higher. Thirty-two percent of participants douched in every study inte
 rval\, and 43.0% never douched. Of the 12\,349 study visits\, 40.2% were c
 lassified as involving bacterial vaginosis. The relative risk for regular 
 douching as compared with no douching was 1.21 (95% confidence interval: 1
 .08\, 1.38). These findings indicate that douching confers increased risk 
 of disruption of vaginal flora. In the absence of a large randomized trial
 \, these findings provide the best evidence to date for a risk of bacteria
 l vaginosis associated with douching.http://aje.oxfordjournals.org/content
 /168/2/188.short\n
DTSTART:20151203T193000Z
DTEND:20151203T203000Z
LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue
  des Pins Ouest
SUMMARY:Perinatal Epidemiology Seminar/Journal Club
URL:/channels/event/perinatal-epidemiology-seminarjour
 nal-club-257031
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