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UID:20251119T132118EST-3984hwU97d@132.216.98.100
DTSTAMP:20251119T182118Z
DESCRIPTION:Indole alkaloids with broad skeleton diversity and important bi
 oactivities have attracted attention of chemists for over a century. Indee
 d\, the polycyclic structures of these natural products provided ideal tes
 t ground for the development of novel synthetic strategies and for the app
 lication of newly discovered reactions/transformations. In this talk\, we 
 will present a unified strategy that allowed us to accomplish the total sy
 nthesis of a number of structurally distinct indole alkaloids from simple 
 cycloalkenes\, emphasizing particularly on the design of integrated one-po
 t domino polycyclization processes.\n\nReferences:\n\nOur group’s recent w
 ork in the field of natural product synthesis\, see: Z. Xu\, Q. Wang\, J. 
 Zhu\, Angew. Chem. Int. Ed. 2013\, 52\, 3272\; T. Buyck\, Q. Wang\, J. Zhu
 \, Angew. Chem. Int. Ed. 2013\, 52\, 12714\; Z. Xu\, Q. Wang\, J. Zhu\, J.
  Am. Chem. Soc. 2013\, 135\, 19127\; O. Wagnières\, Z. Xu\, Q. Wang\, J. Z
 hu\, J. Am. Chem. Soc. 2014\, 136\, 15102\; J.-B. Gualtierotti\, D. Pasche
 \, Q. Wang\, J. Zhu\, Angew. Chem. Int. Ed. 2014\, 53\, 9926\; W. Ren\, Q.
  Wang\, J. Zhu\, Angew. Chem. Int. Ed. 2014\, 53\, 1818\; Erb\, W.\; Grass
 ot\, J.-M.\; Linder\, D.\; Neuville\, L.\; Zhu\, J. Angew. Chem. Int. Ed. 
 2015\, 54\, 1929\; Z. Xu\, Q. Wang\, J. Zhu\, J. Am. Chem. Soc. 2015\, 137
 \, 6712\; Z. Xu\, X. Bao\, Q. Wang\, J. Zhu\, Angew. Chem. Int. Ed. 2015\,
  54\, 14937\; D. Dagoneau\, Z. Xu\, Q. Wang\, J. Zhu\, Angew. Chem. Int. E
 d. 2016\, 55\, 760\; W. Ren\, Q. Wang\, J. Zhu\, Angew. Chem. Int. Ed. 201
 6\, 55\, 3500\; Piemontesi\, C.\; Wang\, Q.\; Zhu\, J. Angew. Chem. Int. E
 d. 2016\, 55\, 6556\; Piemontesi\, C.\; Wang\, Q.\; Zhu\, J. J. Am. Chem. 
 Soc. 2016\, 138\, 11148\; Bao\, X.\; Wang\, Q.\; Zhu\, J\, Angew. Chem. In
 t. Ed. 2018\, 57\, 1995.\n
DTSTART:20180605T050000Z
DTEND:20180605T063000Z
LOCATION:Room 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\
 , 801 rue Sherbrooke Ouest
SUMMARY:Chemical Society Seminar: Professor Jieping Zhu - Diverting Cycloal
 kenes to Polycyclic Indole Alkaloids
URL:/chemistry/channels/event/chemical-society-seminar
 -professor-jieping-zhu-diverting-cycloalkenes-polycyclic-indole-alkaloids-
 286947
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