BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260619T041725EDT-7177cbVaot@132.216.98.100 DTSTAMP:20260619T081725Z DESCRIPTION:\n BRaIN Seminar Series\n\n Brain Repair and Integrative Neurosci ence Program The BRaIN Program of the RI-MUHC is pleased to announce our n ext presentation under the theme:Vision and Cognitive Neuroscience\n\n Spea ker: Dr. Steven Zucker\n\n David & Lucile Packard Professor of Computer Sci ence & Biomedical Engineering\n\n Yale University\, School of Engineering & Applied Science\n\n Founding member of the Centre for Intelligent Machines (CIM)\n\n\n \n\nAbstract\n\n \n\n\n How might one infer circuit properties from neurophysiological data? How do these circuits relate to artificial neural networks?\n\n  \n\n We address these challenges with a novel neural m anifold. It is obtained using unsupervised machine learning algorithms and applied to the mouse visual system. Each point on our manifold is a neuro n\; nearby neurons respond similarly in time to similar parts of a stimulu s ensemble. This ensemble includes drifting gratings and flows\, i.e. patt erns resembling what a mouse would 'see' while running through fields. Our manifold differs from the standard practice in computational neuroscience \, of embedding trials in neural coordinates. Importantly\, for our manifo lds topology matters: from spectral theory we infer that\, if the circuit consists of separate components\, the manifold is discontinuous (illustrat ed with retinal data). If there is significant overlap between circuits\, the manifold is nearly-continuous (cortical data).  To approach real circu its\, local neighborhoods on the manifold are identified with actual circu it components. For the retinal data we show these components correspond to distinct ganglion cell types by their mosaic-like receptive field organiz ation\, while for cortical data\, neighborhoods organize neurons by type ( excitatory/inhibitory) and anatomical layer. The manifold topology for dee p CNN's will also be developed.\n \n Joint research with Luciano Dyballa (Ya le)\, Marija Rudzite (Duke)\, Michael Styrker (UCSF) and Greg Field (UCLA) .\n \n\n DTSTART:20230720T180000Z DTEND:20230720T190000Z LOCATION:CA\, MGH L7 140 SUMMARY:Toward a manifold encoding neural responses in the visual system URL:/cim/channels/event/toward-manifold-encoding-neura l-responses-visual-system-351713 END:VEVENT END:VCALENDAR