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UID:20260619T024653EDT-9051vgG8j4@132.216.98.100
DTSTAMP:20260619T064653Z
DESCRIPTION:ɬÀï·¬\n\nSchool of Computer Science\n\nPh.D. Oral D
 efence\n\n \n\nSpeaker: Tabish Syed        \n\n \n\nAbstract:\n\n \n\nThe 
 study of the geometric organization of biological tissue has a rich histor
 y in the literature. The organization of cells into tissues and tissues in
 to organs has traditionally been described in a qualitative manner. Such q
 ualitative descriptions are largely a result of challenges associated with
  imaging and visualizing biological tissues as well as the lack of computa
 tional power to process large volumes of data. With advances in both imagi
 ng techniques and computational resources\, many formerly speculative idea
 s can now be formalized\, quantified and tested. In this thesis\, we analy
 ze the structure of biological tissue across multiple length scales\, and 
 develop tools and models for such analyses which are grounded in quantitat
 ive methods. Starting with the cellular organization of myocytes in the he
 art wall in part I at the micrometer scale\, through confocal imaging of c
 leared intact tissue\, we go down to the nanometer scale to look at organi
 zation of synapses around an astrocyte in the mouse brain\, in Part II. We
  address long standing biological questions about the structure of an astr
 ocyte and discover new tissue geometry in the heart and synaptic organizat
 ion in the brain. These questions are examined using tools from differenti
 al geometry\, advanced methods for image analysis\, and formulations invol
 ving partial differential equations.\n
DTSTART:20221111T150000Z
DTEND:20221111T180000Z
LOCATION:MC 321\, McConnell Engineering Building\, CA\, QC\, Montreal\, H3A
  0E9\, 3480 rue University
SUMMARY:Cellular Geometry and Tissue Organization in the Heart and the Brai
 n
URL:/cim/channels/event/cellular-geometry-and-tissue-o
 rganization-heart-and-brain-351821
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