BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250511T022553EDT-9682jxI9gP@132.216.98.100 DTSTAMP:20250511T062553Z DESCRIPTION:Thierry Chekouo\, PhD\n\nPostdoctoral Fellow\, Department of Bi ostatistics\, The University of Texas\, MD Anderson Cancer Center\n\nA Bay esian approach for the integrative analysis of omics data: A kidney cancer case study\n\nALL ARE WELCOME\n\nAbstract:\n\nIntegration of genomic data from multiple platforms has the capability to increase precision\, accura cy\, and statistical power in the identification of prognostic biomarkers. A fundamental problem faced in many multi-platform studies is unbalanced sample sizes due to the inability to obtain measurements from all the plat forms for all the patients in the study. We have developed a novel Bayesia n approach that integrates multi-regression models to identify a small set of biomarkers that can accurately predict time-to-event outcomes. This me thod fully exploits the amount of available information across platforms a nd does not exclude any of the subjects from the analysis. Moreover\, inte ractions between platforms can be incorporated through prior distributions to inform the selection of biomarkers and additionally improve biomarker selection accuracy. Through simulations\, we demonstrate the utility of ou r method and compare its performance to that of methods that do not borrow information across regression models. Motivated by The Cancer Genome Atla s kidney renal cell carcinoma dataset\, our methodology provides novel ins ights missed by non-integrative models.\n\nBio:\n\nDr Thierry Chekouo is c urrently a postdoctoral fellow at The University of Texas MD Anderson canc er center under the mentorship of Dr Kim-Anh Do and Dr Francesco Stingo.  He obtained a PhD in Statistics in 2012 at the University of Montreal unde r the supervision of Dr. Alejandro Murua. He also obtained a Master's degr ee in Mathematics in 2004 at the University of Yaounde I (Cameroon) and a Master's degree in Statistics and Economics in 2007 at the Upper National School of Statistics and Applied Economics in Abidjan\, Cote d'Ivoire.  Hi s research interests are in developing new statistical frameworks for anal yzing datasets characterized by high dimensionality and complex structures such as high-throughput genomic\, proteomic and imaging data.\n DTSTART:20151117T203000Z DTEND:20151117T213000Z LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue des Pins Ouest SUMMARY:Special Seminar URL:/epi-biostat-occh/channels/event/special-seminar-2 56278 END:VEVENT END:VCALENDAR