BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250729T172813EDT-9704hOuDzp@132.216.98.100 DTSTAMP:20250729T212813Z DESCRIPTION:Joint integrative analysis of multiple data sources with correl ated vector outcomes\n\nAbstract:\n\nWe consider the joint estimation of r egression parameters from multiple potentially heterogeneous data sources with correlated vector outcomes. The primary goal of this joint integrativ e analysis is to estimate covariate effects on all vector outcomes through a marginal regression model in a statistically and computationally effici ent way. We present a general class of distributed estimators that can be implemented in a parallelized computational scheme. Modelling\, computatio nal and theoretical challenges are overcome by first fitting a local model within each data source and then combining local results while accounting for correlation between data sources. This approach to distributed estima tion and inference is formulated using Hansen’s generalized method of mome nts but implemented via an asymptotically equivalent and communication-eff icient meta-estimator. We show both theoretically and numerically that the proposed method yields efficiency improvements and is computationally fas t. We illustrate the proposed methodology with the joint integrative analy sis of metabolic pathways in a large multi-cohort study.\n\n\n Speaker\n\n \nDr. Emily Hector is an Assistant Professor of Statistics at North Caroli na State University. She obtained her PhD in Biostatistics at the Universi ty of Michigan under the supervision of Peter X.-K. Song.\n\nHer current m ethodological interests are data integration\, especially of correlated\, heterogeneous\, high-dimensional data\, such as spatial data\, estimating equations and the Generalized Method of Moments\, methods that leverage re cent computing and algorithmic developments\, with a focus on divide-and-c onquer\, distributed estimation and inference\, and parallel computing. He r current applications interests are Metabolomics\, Neuroimaging\, Wearabl e devices. https://www.emilyhector.com/\n\nZoom Link\n\nMeeting ID: 843 08 65 5572\n\nPasscode: 690084\n\n \n DTSTART:20210219T203000Z DTEND:20210219T213000Z SUMMARY:Emily Hector (North Carolina State University) URL:/mathstat/channels/event/emily-hector-north-caroli na-state-university-328638 END:VEVENT END:VCALENDAR