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UID:20250810T004155EDT-3648lkacpX@132.216.98.100
DTSTAMP:20250810T044155Z
DESCRIPTION:\nGrâce à la générosité des fiducies Killam\, Le Neuro convoque
  lors d’une série de séminaires des conférenciers d’exception dont les tra
 vaux passionnent ses chercheurs et ceux de l’Université ɬ�﷬. \n\n\nPour
  assister en personne\, inscrivez-vous ici\n\nPour regarder via Vimeo\, cl
 iquez ici\n\n\nLeonard Maler\n\nProfesseur\, Département de médecine cellu
 laire et moléculaire\, Institut de recherche sur le cerveau et l’esprit\, 
 Université d'Ottawa.\n\nHôte: stuart.trenholm [at] mcgill.ca (Stuart Trenh
 olm)\n\nAbstract: Weakly electric fish can find food in the dark using onl
 y their short-range electric sense. There are two mechanisms required for 
 such spatial learning: (a) pattern separation for landmark discrimination 
 and (b) path integration of self-motion signals for learning trajectories.
  The fish use active sensing motions to identify landmarks. The fish used 
 only self-motion signals to rapidly learn efficient trajectories between e
 ach landmark and prey. We found that active sensing and self-motion signal
 s were also essential for mice learning the location of food hidden in one
  of 100 holes within an open maze. The mice did not require any visual lan
 dmarks to find food and could find food in the dark. Given a stable start 
 site\, they needed only self-motion cues and hole checks (active sensing) 
 to learn near optimal trajectories to food. Initial trajectories were rand
 om as were the hole checks. Learning resulted in the mice following a Targ
 et Estimation Vector (TEV) that closely approximated the direct home to fo
 od vector\, and hole checks became restricted and accumulated only around 
 the food site. The mice could successively learn trajectories to two food 
 holes. On a last probe trial\, food was omitted from both food locations. 
 Remarkably\, after finding no food at the second food location\, the mice 
 took a novel shortcut and ran nearly directly to the first food location\;
  this location had last been visited 4 days previously. Shortcutting is a 
 key requirement for a “cognitive map” and this is the first evidence that 
 mice can learn a cognitive map using only self-motion cues. I will directl
 y connect the TEVs and hole check accumulation at the reward site to the p
 roperties of hippocampal (CA1) place cells of rodents that have learned th
 e location of a hidden food site.\n
DTSTART:20241015T200000Z
DTEND:20241015T210000Z
LOCATION:de Grandpre Communications Centre\, Montreal Neurological Institut
 e\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:Killam Seminar Series: Finding Your Way in the Dark: Electric Fish 
 Learn Spatial Maps and Mice Learn Cognitive Maps
URL:/neuro/fr/channels/event/killam-seminar-series-fin
 ding-your-way-dark-electric-fish-learn-spatial-maps-and-mice-learn-358314
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