BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4//
BEGIN:VEVENT
UID:20250505T114721EDT-1649cM1rRv@132.216.98.100
DTSTAMP:20250505T154721Z
DESCRIPTION:Using ecological models in biomedicine\n\nFred Adler\n\nUnivers
 ity of Utah\n\n \n\n Although sometimes scorned as 'people who count anima
 ls\,' ecologists have faced the sheer messiness of their subject to lead i
 nnovation in incorporating complexity and uncertainty into unified modelin
 g approaches.  This thinking is finding new applications throughout biomed
 icine. For example\, accurately modeling the dynamics of disease within in
 dividual patients or across populations is central to predicting outcomes 
 of treatments and strategies to extend life or eradicate disease. But indi
 viduals differ\, with differences including fixed factors like genotype\, 
 predictable factors like age\, and the progression of the disease itself. 
 Evolutionary ecologists have developed a framework to capture the dynamics
  of heterogeneous populations: Integral Projection Models (IPM)\, a type o
 f discrete-time model which use a set of evolutionary and demographic sub-
 models to describe and track how the distribution of a trait\, such as siz
 e\, changes between measurements.  These models conform elegantly to empir
 ical observations\, but despite their power and convenience\, have rarely 
 been used in biomedical science.  I present applications and extensions of
  this method to the course of disease progression in cystic fibrosis and n
 ew work on the interplay between genetic and phenotypic heterogeneity in c
 ancer. \n
DTSTART:20180412T160000Z
DTEND:20180412T170000Z
LOCATION:521\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1Y6\, 3
 655 promenade Sir William Osler
SUMMARY:QLS Featured Seminar Series - Dr. Fred Adler
URL:/qls/channels/event/qls-featured-seminar-series-dr
 -fred-adler-286349
END:VEVENT
END:VCALENDAR