贬别颈驳丑迟:听12听肠尘听
奥颈诲迟丑:听25听肠尘听
Depth :19听cm听
Manufacturer:听MetaMetrics Corporation听
惭辞诲别濒:听惭别迟补惭别尘产谤辞苍听77听
顿补迟别:肠1980听
Dr. Richard Fraser, Director of the Maude Abbott Medical Museum, provides a brief description of the function and/or use of the equipment.
The听MetaMembron听77 is an analog computer made up of 264 transistors and 18 operational听amplifiers that simulates in real-time the electrical activity of a neuronal axon.听It听features several outputs. One gives the voltage across the membrane of the cell; others show, for example, the sodium and potassium currents flowing across the cell membrane. Controls for "poisoning" the membrane with tetrodotoxin (TTX) and/or tetraethylammonium (TEA) are听also听present.听听
Circuit boards听inside听the device.听
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The device was听purchased听by Dr听Michael听Mackey听and听used by him,听Dr.听Ellis Cooper, and Dr. Mladen听Glavinovic听for electrophysiology teaching and by Dr. Michael Mackey听and Dr.听Michael听Guevara for research.听It was called听the 鈥渟quid box鈥� because it is an analog simulation of the electrical behavior of one square centimeter of听squid听axon membrane.
An oscilloscope screen image taken of one experiment shows听a periodic rhythm, each cycle of which consists of several small sine-wave-looking cycles towards the bottom of the trace. These听slowly increase in amplitude until an isolated action potential (the sharp high-amplitude spike)听is generated, after which the next cycle听of the 鈥渕ixed-mode oscillation鈥澨齜egins.听
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Reference:听Guevara, M.R.,听鈥淒isplaced reinjection attractors in an electronic analogue of the membrane of the squid giant axon鈥�.听 In听G. Baier & M. Klein (Eds.), 鈥淎 Chaotic Hierarchy鈥�,听World Scientific, 1991, pgs. 153-164.听